In our practice we use special colours of filled regions to mark some things on plan. For instance for quick schedules we use strange colour combinations. So we could have a pink filled region with a pink outline, but this combination isn't automatically fixed in Revit. Pairing the outline line style of the filled region with the correct filling always needs a lot of our attention... and still then we mostly don't do it right from the first time.
Having those combinations preset in revit would be great!