Dear Gents,
First of all, my best wishes for 2018!!!
This morning I was eager to install this update, but received following message instead:


Log file:
[0130:1C6C][2018-01-05T10:13:33]i001: Burn v3.10.2.2516, Windows v10.0 (Build 16299: Service Pack 0), path: C:\Users\Giovanni\AppData\Local\Temp\{737DC415-B8F8-4AA8-9A10-85DA3E71EE1A}\.cr\2018.2.1.exe
[0130:1C6C][2018-01-05T10:13:33]i000: Initializing numeric variable 'PRODUCT_INSTALLED' to value '1'
[0130:1C6C][2018-01-05T10:13:33]i000: Initializing string variable 'PRODUCT_GUID' to value '{7F4DD591-2264-0001-0000-7107D70F3DB4}'
[0130:1C6C][2018-01-05T10:13:33]i000: Initializing numeric variable 'OPTOUT_KB2918614' to value '0'
[0130:1C6C][2018-01-05T10:13:33]i000: Initializing string variable 'InvParentName' to value 'Autodesk Inventor 2018'
[0130:1C6C][2018-01-05T10:13:33]i000: Initializing string variable 'AdskBundleTitle' to value 'Inventor 2018.2.1 Update (INV22210)'
[0130:1C6C][2018-01-05T10:13:33]i009: Command Line: '-burn.clean.room=C:\Users\Giovanni\Downloads\2018.2.1.exe'
[0130:1C6C][2018-01-05T10:13:33]i000: Setting string variable 'WixBundleOriginalSource' to value 'C:\Users\Giovanni\Downloads\2018.2.1.exe'
[0130:1C6C][2018-01-05T10:13:33]i000: Setting string variable 'WixBundleOriginalSourceFolder' to value 'C:\Users\Giovanni\Downloads\'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleLog' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334.log'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleName' to value 'Inventor 2018.2.1 Update (INV22210)'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleManufacturer' to value 'Autodesk'
[0130:1FE8][2018-01-05T10:13:34]i000: Setting numeric variable 'WixStdBALanguageId' to value 1033
[0130:1FE8][2018-01-05T10:13:34]i000: #(loc.IDS_ERR_BETA_EXIST)
[0130:1FE8][2018-01-05T10:13:34]i000: 1
[0130:1FE8][2018-01-05T10:13:34]i000: Setting version variable 'WixBundleFileVersion' to value '22.20.22791.0'
[0130:1FE8][2018-01-05T10:13:34]i000: Running detect BA function
[0130:1FE8][2018-01-05T10:13:34]i000: >>> Running OnDetect function
[0130:1FE8][2018-01-05T10:13:34]i000: Setting numeric variable 'PRODUCT_INSTALLED' to value 0
[0130:1FE8][2018-01-05T10:13:34]i000: >>> Successfully located target product installation
[0130:1C6C][2018-01-05T10:13:34]i100: Detect begin, 3 packages
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'InvParentName' to value 'Autodesk Inventor Professional 2018'
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1029-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1029-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1029-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1029Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1042-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1042-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1042-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1042Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1041-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1041-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1041-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1041Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1028-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1028-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1028-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1028Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-2052-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-2052-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-2052-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp2052Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-3082-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-3082-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-3082-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp3082Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1046-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1046-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1046-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1046Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1036-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1036-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1036-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1036Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1045-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1045-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1045-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1045Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1033-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1033Installed' to value 5
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-0000-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'TargetProductInstalled' to value 5
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1049-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1049-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1049-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1049Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Setting version variable 'InstalledVersion' to value '22.20.22200.0'
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1040-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1040-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1040-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1040Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-machine extended info for property 'State' for product: {7F4DD591-2264-0001-1031-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Trying per-user extended info for property 'State' for product: {7F4DD591-2264-0001-1031-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Product or related product not found: {7F4DD591-2264-0001-1031-7107D70F3DB4}
[0130:1C6C][2018-01-05T10:13:34]i000: Setting numeric variable 'Lp1031Installed' to value 2
[0130:1C6C][2018-01-05T10:13:34]i106: Calculating patch applicability for target product code: {7F4DD591-2264-0001-0000-7107D70F3DB4}, context: Machine
[0130:1C6C][2018-01-05T10:13:34]i103: Detected related package: {1FA52755-1FBC-0001-0460-7CEA1F3736D8}, scope: PerMachine, version: 4.60.0.0, language: 0 operation: MajorUpgrade
[0130:1C6C][2018-01-05T10:13:34]i101: Detected package: INV22210, state: Absent, cached: None
[0130:1C6C][2018-01-05T10:13:34]i105: Detected package: INV22210 target: {7F4DD591-2264-0001-0000-7107D70F3DB4}, state: Absent
[0130:1C6C][2018-01-05T10:13:34]i101: Detected package: InventorConnect, state: Absent, cached: None
[0130:1C6C][2018-01-05T10:13:34]i101: Detected package: InventorHandleICUninstall, state: Absent, cached: Complete
[0130:1C6C][2018-01-05T10:13:34]i000: Running detect complete BA function
[0130:1C6C][2018-01-05T10:13:34]i000: Running OnDetectComplete
[0130:1C6C][2018-01-05T10:13:34]i052: Condition '1=0 OR VersionNT64' evaluates to true.
[0130:1C6C][2018-01-05T10:13:34]i052: Condition '1=0 OR WixBundleInstalled OR TargetProductInstalled =5' evaluates to true.
[0130:1C6C][2018-01-05T10:13:34]i199: Detect complete, result: 0x0
[0130:1FE8][2018-01-05T10:13:34]i000: Running plan BA function
[0130:1FE8][2018-01-05T10:13:34]i000: Running OnPlan
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1FE8][2018-01-05T10:13:34]i052: Condition '0' evaluates to false.
[0130:1C6C][2018-01-05T10:13:34]i200: Plan begin, 3 packages, action: Install
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleLog_INV22210' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334_{7F4DD591-2264-0001-0000-7107D70F3DB4}_000_INV22210.log'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleRollbackLog_INV22210' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334_{7F4DD591-2264-0001-0000-7107D70F3DB4}_000_INV22210_rollback.log'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleLog_InventorConnect' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334_001_InventorConnect.log'
[0130:1C6C][2018-01-05T10:13:34]w321: Skipping dependency registration on package with no dependency providers: InventorHandleICUninstall
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleLog_InventorHandleICUninstall' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334_002_InventorHandleICUninstall.log'
[0130:1C6C][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleRollbackLog_InventorHandleICUninstall' to value 'C:\Users\Giovanni\AppData\Local\Temp\Inventor_2018.2.1_Update_(INV22210).Setup_20180105101334_002_InventorHandleICUninstall_rollback.log'
[0130:1C6C][2018-01-05T10:13:34]i201: Planned package: INV22210, state: Absent, default requested: Present, ba requested: Present, execute: Install, rollback: Uninstall, cache: Yes, uncache: Yes, dependency: Register
[0130:1C6C][2018-01-05T10:13:34]i201: Planned package: InventorConnect, state: Absent, default requested: Present, ba requested: Present, execute: Install, rollback: None, cache: Yes, uncache: Yes, dependency: Register
[0130:1C6C][2018-01-05T10:13:34]i201: Planned package: InventorHandleICUninstall, state: Absent, default requested: Present, ba requested: Present, execute: Install, rollback: Uninstall, cache: No, uncache: No, dependency: None
[0130:1C6C][2018-01-05T10:13:34]i000: Running plan complete BA function
[0130:1C6C][2018-01-05T10:13:34]i000: >>> Running OnPlanComplete
[0130:1C6C][2018-01-05T10:13:34]i000: OnPlanComplete:GetVariableString:WixBundleExecutePackageCacheFolder== (null)
[0130:1C6C][2018-01-05T10:13:34]i000: OnPlanComplete:BalGetStringVariable:WixBundleExecutePackageCacheFolder== (null)
[0130:1C6C][2018-01-05T10:13:34]i000: OnPlanComplete:WixBundleName== Inventor 2018.2.1 Update (INV22210)
[0130:1C6C][2018-01-05T10:13:34]i000: OnPlanComplete:WixBundleSourceProcessPath== C:\Users\Giovanni\Downloads\2018.2.1.exe
[0130:1C6C][2018-01-05T10:13:34]i000: OnPlanComplete:WixBundleProviderKey== {A8CBC3D3-2200-2010-B79F-C547266D1C0C}
[0130:1C6C][2018-01-05T10:13:34]i299: Plan complete, result: 0x0
[0130:1C6C][2018-01-05T10:13:34]i300: Apply begin
[0130:1C6C][2018-01-05T10:13:34]i010: Launching elevated engine process.
[0130:1C6C][2018-01-05T10:13:34]i011: Launched elevated engine process.
[0130:1C6C][2018-01-05T10:13:34]i012: Connected to elevated engine.
[2A90:25BC][2018-01-05T10:13:34]i358: Pausing automatic updates.
[2A90:25BC][2018-01-05T10:13:34]i359: Paused automatic updates.
[2A90:25BC][2018-01-05T10:13:34]i360: Creating a system restore point.
[2A90:25BC][2018-01-05T10:13:34]i361: Created a system restore point.
[2A90:25BC][2018-01-05T10:13:34]i370: Session begin, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{93d3a8bc-2200-2010-b242-2a19b2a704f8}, options: 0x7, disable resume: No
[2A90:25BC][2018-01-05T10:13:34]i000: Caching bundle from: 'C:\Users\Giovanni\AppData\Local\Temp\{41331CD7-9743-46EB-8CE1-8C27375B5DAA}\.be\2018.2.1.exe' to: 'C:\ProgramData\Package Cache\{93d3a8bc-2200-2010-b242-2a19b2a704f8}\2018.2.1.exe'
[2A90:25BC][2018-01-05T10:13:34]i320: Registering bundle dependency provider: {A8CBC3D3-2200-2010-B79F-C547266D1C0C}, version: 22.20.22791.0
[2A90:25BC][2018-01-05T10:13:34]i371: Updating session, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{93d3a8bc-2200-2010-b242-2a19b2a704f8}, resume: Active, restart initiated: No, disable resume: No
[0130:0658][2018-01-05T10:13:34]i336: Acquiring container: WixAttachedContainer, copy from: C:\Users\Giovanni\Downloads\2018.2.1.exe
[0130:0658][2018-01-05T10:13:34]i000: Setting string variable 'WixBundleLastUsedSource' to value 'C:\Users\Giovanni\Downloads\'
[2A90:23DC][2018-01-05T10:13:35]i305: Verified acquired payload: INV22210 at path: C:\ProgramData\Package Cache\.unverified\INV22210, moving to: C:\ProgramData\Package Cache\{069D1196-1238-4BD5-A205-978B085C24C1}\INV22210_x64.msp.
[2A90:23DC][2018-01-05T10:13:35]i305: Verified acquired payload: InventorConnect at path: C:\ProgramData\Package Cache\.unverified\InventorConnect, moving to: C:\ProgramData\Package Cache\{1FA52755-1FBC-0001-0480-7CEA1F3736D8}v4.80.0\AutodeskInventorConnectPlugin.msi.
[2A90:23DC][2018-01-05T10:13:35]i304: Verified existing payload: InventorHandleICUninstall at path: C:\ProgramData\Package Cache\45F71901528265C72AB51FCF293567EF8D32EE5B\WrapperUtil.exe.
[2A90:25BC][2018-01-05T10:13:35]i323: Registering package dependency provider: {069D1196-1238-4BD5-A205-978B085C24C1}, version: (null), package: INV22210
[2A90:25BC][2018-01-05T10:13:35]i306: Applying package: INV22210, target: {7F4DD591-2264-0001-0000-7107D70F3DB4}, action: Install, path: C:\ProgramData\Package Cache\{069D1196-1238-4BD5-A205-978B085C24C1}\INV22210_x64.msp, arguments: '(null)'
[2A90:25BC][2018-01-05T10:32:44]e000: Error 0x80070643: Failed to install MSP package.
[2A90:25BC][2018-01-05T10:32:44]e000: Error 0x80070643: Failed to execute MSP package.
[0130:1C6C][2018-01-05T10:32:44]e000: Error 0x80070643: Failed to configure per-machine MSP package.
[0130:1C6C][2018-01-05T10:32:44]i319: Applied execute package: INV22210, result: 0x80070643, restart: None
[0130:1C6C][2018-01-05T10:32:44]e000: Error 0x80070643: Failed to execute MSP package.
[2A90:25BC][2018-01-05T10:32:44]i329: Removed package dependency provider: {069D1196-1238-4BD5-A205-978B085C24C1}, package: INV22210
[2A90:25BC][2018-01-05T10:32:44]i351: Removing cached package: INV22210, from path: C:\ProgramData\Package Cache\{069D1196-1238-4BD5-A205-978B085C24C1}\
[2A90:25BC][2018-01-05T10:32:44]i372: Session end, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{93d3a8bc-2200-2010-b242-2a19b2a704f8}, resume: None, restart: None, disable resume: No
[2A90:25BC][2018-01-05T10:32:44]i330: Removed bundle dependency provider: {A8CBC3D3-2200-2010-B79F-C547266D1C0C}
[2A90:25BC][2018-01-05T10:32:44]i352: Removing cached bundle: {93d3a8bc-2200-2010-b242-2a19b2a704f8}, from path: C:\ProgramData\Package Cache\{93d3a8bc-2200-2010-b242-2a19b2a704f8}\
[2A90:25BC][2018-01-05T10:32:44]i371: Updating session, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{93d3a8bc-2200-2010-b242-2a19b2a704f8}, resume: None, restart initiated: No, disable resume: No
[0130:1C6C][2018-01-05T10:32:45]i399: Apply complete, result: 0x80070643, restart: None, ba requested restart: No
[0130:1FE8][2018-01-05T10:32:45]e000: 0x80070643 - Onherstelbare fout bij installatie.
Any ideas???
Thanks in advance...