Which version of Inventor are you running?
Nb.dll is responsible for Engineers Notebook. Disabling it, or not loading it through the use of options via the appropriate xml configuration file leaves Inventor effectively unusable. @TGibson7A8HD - I've sent you a pm on the subject.
Blocking it looks like an option (Event Watcher is only installed with the developer tools). @Frederick_Law Have you tried it? It's a feature of Inventor I can definately live without.
Have you identified what sequence of events lead up to "It prompts itself open all the time and crashes my system"? It would be great to find a repeatable sequence of events the developers could block or at least fix the crash.
A few released back, Engineers Notebook was very close on the menus to something like "New Sketch" and I was forever creating unwanted notes - but it's certainly much harder to accidentally launch in 2023 or 2024.
Peter