Hi Tony,
When I access links from the Fusion360 data panel on WIndows 10, they work on both Chrome and Edge. I'm also able to drag file from the Windows Explorer to the upload dialog, and it works.
I've got a fiew more questions for you.
1. What version of the Chrome browser are you running?
2. Can you please list the exact steps you are trying for drag and drop?
3. What file type are you trying to drag?
4. You mention below "I turned off my av". What does that mean?
Here are the steps I took to get drag and drop to work on WIndows 10;
1. Press on the "Upload" button in Fusion360.
2. Open the Windows Explorer using the button on the Windows 10 task bar.
3. Browse to a design file that Fusion360 knows about (I used a .f3d file).
4. Drag the file from the Explorer to the Upload dialog "Drag and Drop Here" area.
-- Scott