When you use loadable families, Revit pulls (a copy of) them into the project. You can change the location of that family on the harddrive, rename it or modify it without any impact on that project.
When the family is in the original location and yoiu do a reload, Revit rememebers the last location where it was. When you try to reload a moved or renamed family, revit can not find the family and you have to poinbt them to the new location or to the one with the new name.
When you reload a renamed or modified family it will overwrite the one in hte project with the new name/modifications.
So there is no direct link (besides last location) besided the family inside the rpoject and the one in you harddrive folder
Louis

Please mention Revit version, especially when uploading Revit files.