I have three different models, mostely use the Space Navigator as that is what we have in the labs.
I change the zoom/pan behavior so that pan up/down matches pan right/left motion (to me).
I speed it up to about 3/4 (I think slower might cause the twitchyness described above as you then have to apply too much force and you end up over doing it trying to get the model to move.
And like someone else wrote, to me it is exactly like having the actual model in my hand, except that I now have a bionic arm where weight doesn't matter.
Just try running Routed Systems without a 3D mouse, that should be outlawed as torture akin to water-boarding.
I use mine in Inventor, SolidWorks, Creo, Google Earth and every once in a while I try to give AutoCAD another chance (haven't tried with AutoCAD 2014 yet).
We have learned to Calibrate daily, and don't leave anything, not even a sheet of paper, rest against the puck overnight.
On SWx, not that this makes up for canceling a sketch or for not being able to save while in sketch environment, but in Inventor you can pretty much undo back to the beginning of a file and redo back to finished model. In SWx you have to be careful what you Undo because a lot of stuff you can't Redo if you want to.
After a while of jumping from one program to another (I teach all 4 depending on class) I realized I had to simply accept the differences and ignore momentary frustration.
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Autodesk Inventor 2019 Certified Professional
Autodesk AutoCAD 2013 Certified Professional
Certified SolidWorks Professional