Thanks @Anonymous
I had a look at this model and I don't think it is a lost cause by any means.
The first thing to note is that your attempt at lofting is fine in principle but all of these (I think 15 in total) profiles are all connected rather than tangent or curvature continuous so the loft doesn't have very nice transitions between the profiles. This is where the patch environment is great, for getting continuity between profiles but you have to put in a little extra work.
Please note I don't have enough information about the design intent here to make a really nice model. If I did that you may end up with something that does not reflect what you want at all so I have kept your original geometry and made the best of it in the time available to demonstrate that patch is useful even when sculpt may technically be the right approach.
1. The first thing I did was to suppress features on the original loft at about 0.10.
2. At 0.17 you can see the first feature created which is an extrusion (Body 20) of the first profile with a taper angle of -10 degrees. This is to set up the next loft and manage the shape of the lower handle as you will see later.
3. At around 0.34 I have demonstrated another extrusion which will form the top of the lower handle part (Body 21)
4. So this is the important bit for controlling your lofts (especially in the absence of rails). At around 0.44 I have created a loft which is tangent to the surface bodies (Body 20 and 21)I created in steps 2 and 3. The tangency controls the shape of the loft, that is to say that the in order to maintain the tangency to the -10 degree taper (Body 20) in step 2 the loft has to curve (bulge) and taper back to the second extrusion (Body 21) created in step 3. If you wanted to change the nature of that bulge you could use the timeline to adjust the angle of the taper or change the tangency weight or both. Please note that this loft is performed between the edges of the surface bodies created in steps 2 and 3, not the profiles created by the sketches.
5. At around 0.55 I have lofted between the resultant body of step 3 (Body 21) and the next sketch profile (Sketch 35) to create (Body 23). This surface body is tangent to Body 21 but not obviously to Sketch 35.
6. Likewise at 1.06 I have used another loft between Body 23 and Sketch 40. Again using tangent with the Body 23 profile.
7. At 1.28 I have created another surface body using an extrusion (Body 25) from Sketch 42.
8. At 1. 36 you can see another tangent loft between Body 25 and Body 24. Also at around 1.48 the screencast shows how I am turning off sketches to use surface body edges as profiles and not sketch profiles. You probably get the idea by now.
9. At around 2.08. Well you get the idea another connected loft between profiles blah blah blah.
10. At 2.26, Another tangent loft this time between Body 25 and Body 27.
11. At around 2.47 I have created a sketch on the YZ plane, used Sketch > Project > Intersect to get the intersection points of your uppermost sketch (Sketch 52) to the plane and from there arbitrarily sketched a spline for the next step. Please note I didn't take much care over this spline because I don't know what the exact design intent is.
12. So the purpose of the previous step was to demonstrate (at around 3.00) that you can create a surface body using the patch command and an intersecting spline as an interior rail. It isn't really and elegant way of doing this in this model but it does demonstrate what you could do in this type of situation where you don't want a flat surface at the top of your form. If you took more time to create the sketch geometry for this surface it would naturally be better.
13. At around 3.30 I have demonstrated the last loft between the patch surface (Body 29) in step 12 and Body 27.
14. So the last steps were to (rather unnecessarily) reverse a normal and finally to stich the bodies together.
Ok so I hope that all makes sense. I am sorry that I can't spend longer on the videos or show you more techniques but sadly I am on a metered internet connection and these things all add up.
As I said the result is far from perfect but I don't know without more information what the design intent is. One thing is for certain that if you took the time to clean up the sketches for the upper part where the red destroy button is (Sketches 42, 44, 51, 52), you would get better results. There are limitless possibilities.
Another thing to note is that the sharper edges of the upper part would usually be cut from the lofted body. That is to say that that the lofted body would be a smooth organic shape and flats would be cut into it using extrusions or sweep or whatever is appropriate for making flat surfaces. I can demonstrate this in another video if that helps.