I assume that you are using AutoCAD Architecture, and not plain AutoCAD, based on you posting in this forum.
Do you have access to out-of-the-box Imperial-unit content, such as that provided in the US Imperial content? If so, best practice would be to start files with one of the out-of-the-box Imperial template files, as you will start out with all the right settings for Imperial-unit drawings, and would only need to set your annotation scale to 1/4" = 1'-0" and then create a Viewport on a layout that is scaled to view the model at 1/4" = 1'-0" (1:48). I am assuming that you plan to follow standard practice of drawing all "real world" elements in model space at their full size, and handle the scale of the plotted output through the scale factor of a Viewport on a layout.
If you have existing drawings that were not started with an Imperial-unit template, you may be best served by starting a new drawing with an Imperial-unit template, and then INSERTing/EXPLODing your file within it, particularly if the file was not created in AutoCAD Architecture, as that will get you the out-of-the-box display settings, as well as the units and other settings. But you could manually change the drawing to Imperial units: