I've taken the sample from the API help that demonstrates creating a new title block and added a line at the bottom that inserts and image. You have a choice of linking or embedding the image (the third argument in the Add method) . If you link it, you'll need to make sure the image is somewhere in the project so Inventor can find it.
Public Sub CreateTitleBlockDefinition() ' Set a reference to the drawing document. ' This assumes a drawing document is active. Dim oDrawDoc As DrawingDocument Set oDrawDoc = ThisApplication.ActiveDocument ' Create the new title block defintion. Dim oTitleBlockDef As TitleBlockDefinition Set oTitleBlockDef = oDrawDoc.TitleBlockDefinitions.Add("Sample Title Block") ' Open the title block definition's sketch for edit. This is done by calling the Edit ' method of the TitleBlockDefinition to obtain a DrawingSketch. This actually creates ' a copy of the title block definition's and opens it for edit. Dim oSketch As DrawingSketch Call oTitleBlockDef.Edit(oSketch) Dim oTG As TransientGeometry Set oTG = ThisApplication.TransientGeometry ' Use the functionality of the sketch to add title block graphics. Call oSketch.SketchLines.AddAsTwoPointRectangle(oTG.CreatePoint2d(0, 0), oTG.CreatePoint2d(9, 3)) Call oSketch.SketchLines.AddByTwoPoints(oTG.CreatePoint2d(0, 1.5), oTG.CreatePoint2d(9, 1.5)) Call oSketch.SketchLines.AddByTwoPoints(oTG.CreatePoint2d(0, 2.25), oTG.CreatePoint2d(9, 2.25)) Call oSketch.SketchLines.AddByTwoPoints(oTG.CreatePoint2d(4.5, 1.5), oTG.CreatePoint2d(4.5, 2.25)) Call oSketch.SketchLines.AddByTwoPoints(oTG.CreatePoint2d(3, 2.25), oTG.CreatePoint2d(3, 3)) Call oSketch.SketchLines.AddByTwoPoints(oTG.CreatePoint2d(6, 2.25), oTG.CreatePoint2d(6, 3)) ' Add some static text to the title block. Dim sText As String sText = "TITLE BLOCK" Dim oTextBox As TextBox Set oTextBox = oSketch.TextBoxes.AddFitted(oTG.CreatePoint2d(4.5, 0.75), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter sText = "Static Text" Set oTextBox = oSketch.TextBoxes.AddByRectangle(oTG.CreatePoint2d(0, 1.5), oTG.CreatePoint2d(4.5, 2.25), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter ' Add some prompted text fields. sText = "<Prompt>Enter text 1</Prompt>" Set oTextBox = oSketch.TextBoxes.AddByRectangle(oTG.CreatePoint2d(4.5, 1.5), oTG.CreatePoint2d(9, 2.25), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter sText = "<Prompt>Enter text 2</Prompt>" Set oTextBox = oSketch.TextBoxes.AddByRectangle(oTG.CreatePoint2d(0, 2.25), oTG.CreatePoint2d(3, 3), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter ' Add some property text. ' Add the property value of Author from the drawing sText = "<Property Document='drawing' FormatID='{F29F85E0-4FF9-1068-AB91-08002B27B3D9}' PropertyID='4' />" Set oTextBox = oSketch.TextBoxes.AddByRectangle(oTG.CreatePoint2d(3, 2.25), oTG.CreatePoint2d(6, 3), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter ' Add the property value of Subject from the drawing sText = "<Property Document='drawing' FormatID='{F29F85E0-4FF9-1068-AB91-08002B27B3D9}' PropertyID='3' />" Set oTextBox = oSketch.TextBoxes.AddByRectangle(oTG.CreatePoint2d(6, 2.25), oTG.CreatePoint2d(9, 3), sText) oTextBox.VerticalJustification = kAlignTextMiddle oTextBox.HorizontalJustification = kAlignTextCenter ' Add an image. Call oSketch.SketchImages.Add("C:\Temp\Img.png", oTG.CreatePoint2d(0.25, 1), False) Call oTitleBlockDef.ExitEdit(True) End Sub