I did have a situation where the reason my edits would not stay was that the Factory add-in was loaded, I can give you a long list of steps you can follow to get them to stay in your Quick Access Toolbar. The strange part is some tools would stay and some wouldn't, so it is selective of the ones that get reset. I have logged this issue with Autodesk and they are hoping to have a patch out to fix it soon.
Right-click on the ribbon and select “Customize User Commands…” from the Part environment.

Add any commands to the right-hand side that you want to be in the QAT (eg check-in, check-out and iTrigger)

This adds a new “User Commands” Panel to whichever TAB you were on when you clicked on “Customize User Commands…”

Now Right-Click on these one at a time and add select “Add to Quick Access Toolbar” and they will all be added to the QAT


Now you can hide your “User Commands” Panel by Right-Clicking and selecting “Show Panels” and then selecting “User Commands”

You will need to do this for all environments ie: Drawing and Assemblies
If this solves your issue please mark this posting with the "ACCEPT SOLUTION".
If you like something that was said or if it was helpful, Likes are appreciated. Thanks!