Thought I had a better solution to provide a more true grill effect with partial holes, but it turned out to be a lot more steps in practise than I thought. Either way, here's how I did it.
Another way to do it would be to do all the holes first and then just extrude a 2mm border over the top to fill in the ones you don't want. That would be much quicker than the following.
Note: Using extrusion for your holes will not get you a drill call out in the drawing environment.
Another way is to extrude the holes as a new solid.

Pattern them as a new solid

Use combine to combine all the circle extrudes. (this speeds up the split command)
You can drag select and the ctrl click to get rid of the main plate

Use offset to do a 2mm border

Extrude that as a surface

Use split tool to cut your 2mm border into the holes.

Use delete face in lump mode to get rid of the extra ones.

Finally use combine to subtract the extrusions

finished part


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