How to loft irregular shape to circle.
Break it down to smaller tasks, New sketches help with shaping.
Origin should have been in the centre of the model. Who knew the two holes in the plate are not symetric.
First iteration may not be what you want.
Further review of your construction, use symmetry where possible.
Blue, orange and white sketch articles will keep you awake at night.
Move Tool should not be used, build in place, and let Fusion do the hard yards.
A 6-inch pipe would not be 143.5 dia.
My example file, with your measurements.
Might help....
Looking at the timeline of your design, it is very inefficient and causes you to work harder than necessary.
As has been mentioned already, if something is symmetrical, the origin should be in the center.
Maybe only sketch and design half of it and then mirror features or geometry.
I can create a screencast if you are interested.
Can be a 1/4 sketch, surface Loft with tangency, and later 2 mirrors. (File was supplied)
Might help...
