@Anonymous If you used the save command, the applog files contain a record of what has been saved and sync'd with the cloud.
Could you post a copy of your diagnostic log files along with the name of the design of interest?

The auto-save does have a default interval set by default. There may be something in the recovery (see below) directory that may be useful.
Above you mentioned that the "work is gone." Can you be more specific about what that means? Does that mean that you're missing components or that the toolpaths are no longer generated? I don't understand what is missing, exactly.
From your description, it sounds like the design is there and not lost. Thanks in advance for the clarification.
Does the version that is there look like a previous version of the design? Could you have accidently promoted a previous version or something?
You can learn about working with versions in Fusion in the below link.
help.autodesk.com/view/fusion360/ENU/?guid=GUID-16B4A3A9-9188-4193-95CD-00371D595EC0
Do you know if there are pending uploads that need to be synced with the cloud from a particular computer?
Have you checked the upload Q folder?
Have you check the recovery folder?
Is the design just missing toolpaths?
I'd also note in the CAM workspace that you can "lock" a tool path by using the Protect option. This will prevent you from having to generate the toolpath upon re-opening a design.

I hope that helps. If not, please share the diagnostic log files so we can take a closer look and help. Any questions, just let me know.
Thanks,
Nathan Chandler
Principal Specialist