I released a YouTube video on batch plotting last week that has what you're looking for.
https://youtu.be/4KQowXzgj1Q?si=DwS7cmv89F9BtjqI
The last segment explains how to use Page Setup Manager to create layout definitions that are reusable.
While the video focuses on using Batch Plot (or Publish), once you create the Page Setups, you can simply select them in the regular Plot dialog in the very first drop down.
So the process would be, create your Page Setups per the video. Then when making a new layout, you can start the plot command and select that page setup from the dropdown.
Ideally you would then save the drawing where you did all of this as a template. If you do, then you can make a new layout simply by right-clicking on a layout tab, selecting New Layout from Template, and get it done that way.