Honestly, I don't know if this will work, but "in theory" it seems that it should work.
"Should I place the C:/Users/SamPesiridis/...... etc. in other users Support File search Path in Autocad??
Sort of...
When a Profile is exported from one user's AutoCAD and then imported into another user's AutoCAD, any paths stored in the Support Files Search Path (SFSP) that point to user-specific folders and appear there with that user's username are actually not stored that way (in the Windows registry). They are stored (not visible to the user thru Options) as a replaceable parameter. AutoCAD "resolves" the variables for display in Options.

So, the first path in the image above is actually stored as %UserProfileFolder%\Appdata\etc., wherein the replaceable parameter (a Windows environment variable, much like an AutoCAD system variable) changes automatically based on the username of the logged in Windows user.
Unfortunately (or maybe it's fortunate), you can't enter the path this way in Options. It has to be done by importing a profile that was exported from a user that has the SFSP set up the way you want it. (Importing a profile makes changes to the Windows registry, which are then "read" by AutoCAD when it is launched. This is when the replaceable parameter is converted to an actual path.)
"Then you mention remove it from the tool macro. How will it then load the pdf??"
"Is there a command that will overwrite my userprofilefolder in the tool macro to theirs???"
This part is where I'm stretching the theory a bit, because I have no previous experience with this particular type of macro. In AutoCAD generally, when filenames are referenced without explicitly stated paths, AutoCAD "looks" to the SFSP (or other paths stored in Options depending on the context) to "search" for the referenced file.
I know this works in several scenarios in AutoCAD, but I don't know if it works in the case of the type of macro you are dealing with.
I will try to duplicate your conditions and do a test of my own, but hopefully you will be able to put this all together and discover the answer before I do.