Hi,
>" that the Defpoint layer is not to be used by the users for any purpose"
This is not a rule of the program, it is the (very) good advice from professionals!
Of course you could use the layer, but the layer does not behave identically to others and the normal user does not know these subtleties.
Even professionals don't always think about it when AutoCAD behaves in a completely unusual way, but the reason lies somewhere else entirely, such as a frozen system layer
If you set yourself a rule not to use the layer, then you won't even think of locking or freezing it.
That's why I say: Just don't use it, then you'll be less likely to freeze it (because why should you freeze it if you don't have anything on it)
(Yes, I use them, sometimes - but I know the effects and I also think about them when problems arise)