At work I download a dxf file and copy the auto-created drawing from that file into our built out template in order to finish a project. There are times when I won't see issues with the drawing into getting it into Autocad, and fixing it elsewhere and then re-downloading a new dxf and copying it again is the quickest solution. Often though, when I paste the new drawing into the master template, though I've copied the new drawing, what gets pasted is the first drawing that I copied, not the new drawing.
Put another way, I copy and paste Drawing A from dxf to master template and find issues with Drawing A. I go back to the source, push a few buttons to make the quick fixes and get a new dxf. Copy (ctrl+c) on Drawing B, go to the master template and when I hit ctrl+v, what pastes is still Drawing A. I can go through the same steps and get a Drawing version C and D, but always what gets pasted is Drawing A. I've tried closing AutoCAD completely between copy and paste cycles. And I've tried wiping the computer's clipboard, neither of those works.
The drawing in the dxf file does start all grouped, if I explode it enough, at some point it will work, but sometimes that will cause other issues. I am using AutoCAD 2018LT, but this is something I've experienced across multiple versions of AutoCAD.