Not at all...
I've been using a PSpace for titleblocks and viewports to display schematics and mechanical layouts. As long as you set up your titleblocks correctly, use 1 dwg per page in the project, signal references and titleblock information will update without issues. Mechanical layouts are always drawn 1:1 and you avoid a scale up or down percentage to get the the mechanical layouts to fit the page size, this is easier to do in PSpace and use scaled viewports.
IMO, PSpace allow more flexibility to present your dwgs...
Hope this helps!
Omar
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