Your file is saved in AutoCAD 2000 format, but when I opened it in AutoCAD Architecture 2017, I was told there were future objects in the file, suggesting that at some point it had been opened in the 2018 (or later) release.
I then opened the file in AutoCAD Architecture 2020, and was able to save as to the 2000 format in approximately 15 seconds and the 2018 format in a second or two. You mention that it takes "longer" - are you seeing save times that are significantly longer than mine?
Is there a reason why you are saving back to the 2000 format? You may be able to reduce the save time by saving to the native format for 2017, which is the 2013 file format. It will not make much difference whether the layers on which you have hatches are frozen or thawed; they have to be saved to the file either way. Freezing the hatch layers will improve drawing performance, particularly during zooms and pans, since there will be less geometry to recalculate. Breaking the file up into separate files and then recombining them by externally referencing the other files in each one may improve the save time, as you would only be saving the contents of the open file (including the external reference data), not all of the objects in all of the files. The overall size loaded into memory will still end up being roughly the same, so opening times and the performance probably would not change much, since it all still has to be loaded in.
David Koch
AutoCAD Architecture and Revit User
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