I am having the same exact problem and seek a solution. On only 1 computer in the office (mine); when trying to open a drawing from inside Revit (File>Open), the opening process will reach about 73%, and close unexpectingly without a notice of error. Like said before, the programs closes as if it had not been running in the first place. As mentioned, I can open the files through Windows File Explorer, but endure periodic crashes when working on the file (not sure if i can technically call it a crash as those typically warrant some sort of system acknowledgment). These symptoms lead me to believing that we're dealing with virtual memory or RAM issues. Is this correct, and is there a way to solve this issue? I'm already working with 3gbRAM, which by all means should be sufficient for the 32-bit application. Thoughts...Ideas? Or do i simply hope that this bug is corrected in the first service pack for Revit2010