Just like you can't modify the Copic Brush Set because it doesn't show "Advanced" options, I would like Autodesk to add that same feature for Custom Brushes.
I'm a guy that always keeps backups of everything, and of couse this means that I own backups of my Custom Brushes.
So, one day I was using the Brush Puck, and I was testing the "Change Opacity/Flow" option instead of just the "Change Size Only" option... soon after all my brushes wouldn't work as expected because I didn't noticed that I changed the Flow of my brushes with the Brush Puck.
I've disabled that option ever since, and loaded my brushes once again.
Although this is not a problem, as you can literally turn off the "Change Opacity/Flow" settings from the Brush Puck, adding the feature of locking the brush settings might come useful when sharing brushes with other uses, as they'll work the same everytime because it's features can't be changed.