Okay so that's a strange design process, placing equipment and pipes before you have a design and know where things are and what direction they are flowing/falling/rising.
Ideally you would place the equipment/terminals in the correct place and then work towards or away from them, the elevations of the connectors on the equipment/terminals then determine the start/end elevations of your pipes.
You can try using the slope adjustment tool but if the pipes are anchored by connections to equipment you probably won't be able to change the slope angle much and almost certainly won't be able to change the slope direction, so you would need to break those connections first.
Tab-select to select a whole pipe run and then select the Slope tool:

If you want to reverse the slope direction you will first need to use the Slope tool to remove the existing slope:

Then tab-select again and select the Slope tool again:

Now in the slope editor you should see the Slope Control Point enabled. toggle it to the end (or if you have branches the location) which you want to be the lower end of the slope:

...and then apply the slope:

Slope is now reversed for the whole run.
Its not fool-proof though, it won't work in every instance depending on how your pipe run is laid out - you will probably end up having to disconnect sections to apply slope and then reconnect them.
Hope this might be of some limited help.