AutoCAD 2022 and ASP.NET 8.0.12
Why ASP.NET version has anything to do with AutoCAD? ASP.NET is a type of web application that runs on server side, typically remotely, and users interact with it with an web browser in general via HTTP protocol. ASP app is built with MS .NET technologies, currently it should be on .NET 6/7/8/9. Again, ASP.NET installs/runs in backend/remote web server computer, updating it with v6 to v8 (I assume you mean: from .NET 6 to .NET 8) does not have anything to do with AutoCAD installed in CAD user's computer.
I suspect you really mean is "upgrade .NET 6 to .NET 8 on user computers where AutoCAD are used. Regardless how the .NET 6 to .NET 8 upgrade is done, AutoCAD 2024 or older requires .NET Framework. Installing .NET Core (5, 6, 7. 8. or 9) should not change that. AutoCAD 2025 requires .NET 8, which will be installed with Acad2025, if the computer does not have it installed).
It is not clear if your AutoCAD 2022 uses custom .NET plugins, which should be based on .NET framework. It is also not clear that when you say "upgrade", does that include rebuild the custom .NET plugin with .NET 8 (if you did, the code/plugin will not work anymore, because Acad2024 or older cannot use code that built with .NET core).
Again, because you referred the "upgrade" to an irrelevant term "ASP.NET", it is really not clear what "upgrade" means. Also, if your issue is just because installing/uninstalling something that stops AutoCAD working, then you posted in wrong forum: this is about AutoCAD .NET API programming topic, not about AutoCAD installing/using/managing issues.
