That sounds like an intense model for sure.
I would recommend splitting the model up. keep the chunks manageble, around 50,000sf should load quickly. When the model is loading it is pushing everything to the RAM (random access memory) so it has to download portions of all that data to visualize it in 3D form. Less data = higher performance.
I would also agree with your opinion on Glue. It offers a huge advantage to coordinate with the entire team. It will be exciting to see it further developed now that it is becoming more mainstream.
Cheers