For a frame like the 2nd pic, I would use FG.
@swalton pretty much nailed it.
I hardly use 3d sketches since they have a tendency to go out of whack down-stream when things change near the end of a project. So almost all my work w/FG is done using 2d sketches on WorkPlanes. I try to use the least amount of WorkPlanes and sketches as possible, esp. on a big frame, in which case I usually divide it into sub-assemblies.
Any custom platework I make with non-FG parts and appropriately constrain, or Derive the frame sketch into the part and use it as a reference so the part can be grounded to the origin of the assembly.
If you're slick about it, you can add wires (sketch lines) to a plane that isn't on the right plane for a member, and then offset the member to get it where you need it to go.
If there are small stray parts that would require a lot of WorkPlanes and sketches, I usually make them all in a 3d sketch at the very end of the wireframe part and connect them to existing geometry. That saves a lot of extra WorkPlanes and sketches. Also, I try to limit the FG to parts that don't have assembly features, such as holes and cuts. That's what happens with stairs and railings. I'll make the stairs stringers and platform from custom parts, and the railings with FG. Makes it easier to detail and to locate and plan the railing geometry.
Now if you detail every part, then you have to make provision for that using ViewReps (or now I believe you use ModelStates). Then you have to make provision for drawing PartsLists and detail views with the labels. So it can get involved if you have a lot of detailing to do. This is where you do your planning ahead of time if possible, which determines how you structure the project.
There are many ways to do this, but since your pic2 frame is simple, the quickest is probably using FG. The more experience you have, the more versatile you become with how you make frames.
... Chris
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