Thanks @sublicut ,
So I found the smoking gun, but the question is 'what is causing this error'
E NEUTRON_BUG_ALERT(XML: Cannot save file - Failed to save XML file ***/Local/Autodesk/Autodesk Fusion 360/***/OfflineCache.xml. Exception: unable to open file '***/Local/Autodesk/Autodesk Fusion 360/***/OfflineCache.xml')
This file being unable to be opened is indeed the root cause. My two best guesses right now are - something with the permissions may have changed? This folder location does require admin level permissions; and its possible you no longer have write permissions to the folders under 'appdata'.
One thing to try -- can you manually navigate to this location and delete the file? The file is in:
C:/users/username/appdata/local/Autodesk/Autodesk Fusion 360/<alphanumeric folder name>/.
If it lets you delete it, try to restart Fusion. I'm very curious why the file cannot be opened when Fusion runs.
OR
Multiple Fusion instances are running at the same time. This can be solved by Task Manager, restarting the computer etc.
Let me know your findings.
James Youmatz
Product Insights Specialist for Fusion 360, Simulation, Generative Design