I am also having this issue. My simulation precheck says everything is good, and it seams to upload to the cloud successfully, but then it fails.
Here is my log file. There may be other simulations in it, but the last one is at least relevant. I didn't want to edit it because I don't know what is needed or not.
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 09:02:52 _____
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:01:31 _____
Error: Please inspect mesh failures.
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:01:32 _____
29798 Tetrahedra : 100.0% of elements (100.0% of volume)
Face Angle min: 13.1, max : 136
Dihedral Angle min: 13.3, max : 163
Worst shape ratio : 7.46 on element 21112
Worst aspect ratio : 5.06 on element 13484, shortest edge: 0.000611, longest : 0.00727
Lowest collapse ratio : 0.186 on element 21112
Worst Jacobian ratio : 1 on element 1
Base mesh: 7257 nodes, 29798 elements
Job has finished successfully. Receiving results.
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:02:46 _____
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:02:46 _____
30229 Tetrahedra : 100.0% of elements (100.0% of volume)
Face Angle min: 18.5, max : 141
Dihedral Angle min: 14.8, max : 159
Worst shape ratio : 8.9 on element 15882
Worst aspect ratio : 3.22 on element 30150, shortest edge: 0.000566, longest : 0.007
Lowest collapse ratio : 0.169 on element 15882
Worst Jacobian ratio : 1 on element 1
Base mesh: 7343 nodes, 30229 elements
Job has finished successfully. Receiving results.
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:05:21 _____
Motor Mount GD v6: Simulation Model 1 - Study 1 - Shape Optimization
_____ 2022-01-19 10:05:22 _____
Document is being uploaded to cloud storage. Cloud job is pending.
Starting solve
Error: Unable to start the solve - Error("HELIUM_ERR"): Internal Server Error
I've also attaches a photo of the project I am trying to simulate. I have already run several different studies using similar models so I'm at least 10% sure my constraints and loads and everything else are correctly configured. Maybe 9%.