I also encounter the same issue with windows 11 and 4k display at 150 % scaling. I ended up with HighDPIScalling and scaling override settings enabled.
Settings screenshot:
With this settings canvas is properly rendered and text is mainly scaled and crisp, no icons are scaled. But only text is scaled, not the space for the text, so with scaling factor higher than 150 % text does not fits to the dedicated space. It is so lucky for me that I use only 150 % scaling.

Text in data panel and all its context menus is not scaled. Navigation bar is not scaled, as any other icons but I find it especially tiny and hard to hit, see how it should look at 150 scaling and how it actually looks.

I could work with that, but these settings are cause eye strain after couple of hours and now I am happy that I use Fusion 360 only few hours per month.
I also fing it very frustrating that this very essential issue is not solved in 5 years.
UPD: To see, how this (and all others from posts above) screenshots actually looks, you have to set your display scaling to 100 % or save this images and open it with a viewer or editor that could display images at 100 % scale. In paint it displayed correctly.