Hi Jeff
Yes, I want to have a manufacturing model that takes parts from the model workspace, applies a simple change (reducing the bore by 1mm, getting rid of holes) and then nests it. I want this to be "robust" in the sense that I can make a small change to the original model (e.g. changing sheet thickness) and the manufacturing edits will update automatically.
This doesn't seem to work. I was pleased to find that each nest is a manufacturing model and I could edit it to remove holes etc (push-pull to fill them). I wasn't able to change the external dimensions as parts would overlap, but it's a start - or so it seemed. If I edit the manufacturing model though, the nest is regenerated and all the edits are forgotten. So one has to be ever so careful to turn off "Automatically calculate nest" and never to change the original geometry and have to re-nest it. In fact "Automatically calculate nest" turns itself back and I keep finding F360 is unresponsive for a few minutes while it re-nests. Not helpful when I'm waiting to make a further change! It also seems to re-nest for the most trivial of changes (e.g. changing sketch visibility) - totally unnecessary - and I get the impression it is regenerating every sheet when I have only changed a component on 1 thickness of sheet.
I don't find it at all user-friendly. Either I am missing something very basic in terms of work-flow or it needs a lot of UI development.
Anyway, it's now 8 pm. I was up early and I have spent the entire day lovingly eradicating holes, tweaking dimensions of bores that will later be machined etc. Not helped by finding that Component Sources had somehow got confused about the number of items required and given me too many of one and not enough of another [this would be more obvious if the sources tree didn't expand over about 30 scrolling pages - there is no way of only showing the non-ignored items]. So yesterday I drove hundreds of miles to pick up the metal and now I find I've got the wrong size. Fortunately I have managed to re-position things onto different thickness material so I can cut the bits I need but I could do without the hassle.
At the end of the day I have exported 15 DXF files for the different thickness sheets. The files contain about 90 different shapes and 2-8 copies of each. Marvellous.
I then switched to a computer with a 2D CAD program and opened one of the DXF files. ARRGHHH! None of the manufacturing edits have been included in the export. So the cutting pattern in F360 looks like this:

(the smaller flanges have bolt holes removed and bore reduced for machining after laser-cutting) but the DXF file looks like this:

The holes are there! And the bore is the original diameter! That's a whole day of my life I won't get back again and I can ill afford to lose the time on an exceedingly urgent job.
I'm not sure what the point of the manufacturing model is, if one cannot export what's visible on screen. I cannot be the first person with problems like this.
I really do not want to have to "fork" a complete set of models and change their dimensions just for the nesting. I would prefer to have a model that can be edited periodlcally and relates to both the 2D drafting and the laser-cutting nests. I suppose I will have to "corrupt" all my model files with the cutting rather than machining dimensions, generate a new nest, save the DXF files, then roll back to earlier versions of the model files for the 2D drafting. This isn't an efficient way of working....if I need to change the design I will have to mirror the changes in both the machining and the cutting versions. [While I'm on the subject, the 2D drafting has its own hassles. Any trivial change like opening a model sketch triggers a new version "*". If I save the model file, the drawing updates and many of the sheets are greyed out until I click on them to refresh. All very time consuming when the parts have not been edited at all].
Roger.
PS. Ideally one would make these changes to a manufacturing model in the original design file. One could envisage multiple manufacturing models, one for laser cutting, one for rough machining, one for grinding etc. One should then be able to pick which of these variants is used for nest preparation, which for making 2D dimensioned drawings etc. Currently I can make a manufacturing model in each part file but there is no way of nesting this so it doesn't seem to be much use.