@jeff_strater - Almost, but not completely correctly understood. Hopefully I am more clear with extra info.
The components imported from STEP in my model are in this case LEDs and stepper motors, which I positioned with circular arrays and via sketches on a custom shaped PCB. The clearances around these components are determined by projecting them on the PCB shape sketch, creating an offset and have the outline of the PCB follow this offset. I will not be designing the actual PCB (since I am not capable of doing so; mechanical is my field); an electrical engineer will do this in another software. He will respect the shape of the PCB I am providing and requested those clearances.
I never work in direct modelling mode, although I did clean up the imported STEP models that way before using them in my assemblies. Not much more than stitching though, to get closed bodies if needed.
I exclusively work parametrically to generate geometry, via sketches rather than solids or Derived geometry. (nearly) All my components are fully constrained. During development I do sometimes have the sketches of components or features (e.g. extrusion length) refer to each other. That is something I want to get rid off when the model is mature and several components need to be frozen/released/ordered. In other softwares I would 'isolate' sketches; breaking links to anything referenced and <Fixed> to keep everything fully constrained. Similar story for isolating features. That is what I am trying to achieve here: kill all links to their environment of some components which need to be frozen, while some others can still be associative to others.
The only (workable) solution I could find to achieve this, was to <Save copy as> and (re-)import the geometry. I am still hopeful that I overlooked something trivial in the F360 functionality, since this workaround feels a bit like removing a wisdom tooth - rectally. Overly complex, not really giving the desired result and a lot of mess.
My main motivation for making the STEP files local, was that you have more freedom for assigning materials/appearance, as well as reducing the frustration of the reduced feature set available when editing in place or the hassle of working in another tab and having to update the parent model.
The duplicate dimensions likely come from having two similar assemblies in my model, the base of which was created via copy-paste. Two identical enclosures with some same and some similar components inside in this case. Exporting both separately and getting them back in, did result in the same parameters with _1 or _2 added to their name. That gave me the confidence that there would be no duplicates. But exporting to CSV showed that there were a bunch. Trying to solve that via the F360 internal <Change Parameters> tool resulted in the trouble I started this discussion for.
Another odd thing I noticed, is that not all parameters in the CSV file have "-double quotes around them, even if they contain a space or a formula. That doesn't seem very reliable to me, since the software then doesn't know where the Expression stops. Someone made a remark about this on the download page of the CSV tool.