Adding something like the MeshFusion support into the Fusion 360 Sculpt tool would allow one to get the best of two worlds, working like with solids but in a T-spline environment!!
It can be done with SubD models, so it should hopefully be possible to do with T-splines, as both of them can be created from Nurbs.
Check the video for a better idea of how this could work!
https://www.youtube.com/watch?v=kjzfhbW2hNY