Minor disclaimer - I'm not certain that this was a timeline propagation issue /but/ last night I had a bit of an issue with a modestly complex design.
We embossed a bit of text onto a component, went forward with a bit more design work then went back to make some changes to the text. Basically every change to the sketch (including things like adding a line or moving / editing text) was causing Fusion 360 to hang for ~1-2 minutes. I /think/ this might be due to the changes propagating forward through the timeline, in which case, it could be avoided by allowing the user to make changes and waiting until they are done to propagate (at least if that's the issue, that would coalesce a bunch of delays into a single one).
Probably not worth sharing but I actually got annoyed enough to record a ~7.5 minute video showing more or less add line (1-2 minutes of beachball) edit text (1-2 minutes of beachball) move text (~1-2 minutes of beachball) and so on.