Happened to me a few times.
I import a large mesh or an .svg with to many points and I try to select everything or use somehow the too complex feature.
Fusion is grinding the data but the UI is not responsive anymore. Activity monitor shows Fusion as "Not Responding".
Fusion should separate the UI thread from the processing thread and allow the user to "break" the last attempted operation (warnings and all).
Only solution I found to be able to get back to my work is to kill Fusion and open the last recovered version of the project I'm working on.
Running on an old mac -
2 x 2.66 GHz 6-Core Intel Xeon
16 GB 1333 MHz DDR3
Radeon RX 580 4 GB
Imported mesh I tried to select has 10K faces.
Thanks