• Possible:
Constrain a point/endline to the midpoint of another line/arc
Constrain 2 lines' midpoint to be coincident (eg: symmetrical cross)
• Not Possible:
Having a line (A) going through the middle of another line/arc (B) and being constrained to it.
• Current Solution:
Create a split line (A1/A2) with 2 collinear lines, and constrain the meeting point with the midpoint of the other line (B).
• Bonus:
Making a midpoint/centerpoint a selectable reference would also allow any other type of constraints (aligned, concentric...)
This exists on every other CAD softwares I used in the last 10 years...