I do not have the Mac version, but based on the link below, Profiles are not part of ACAD for Mac (at least when this was published)

Maybe someone will come along later and confirm that has changed.

https://www.cadnauseam.com/2010/09/01/autocad-for-mac-whats-missing/

Here are a couple of more threads where the answer seems to be No.

[1] [2]