Plot styles not working at all in an old file that has .ctb setup.

When I change the plot style in the layout Page Manager, the layers still say that the Plot Style is By Color, and does not list the new plot style that was changed.  Sometimes it comes back when I open/close the file and autoCAD but it's really inconsistent. 

I have been dealing with this for about a half an hour and I just want to print this file in B/W the way the .ctb is setup.  It will only print using the color lines from the layers, even though I have tried to assign multiple different new .ctb files.