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I think this code should work:

Dim FilePath As String = "C:\Projects\testing.xlsx"
Dim SheetName As String = "This_Sheet"
Dim Column As String = "B"
Dim Row As Integer = 3

GoExcel.Open(FilePath, SheetName)

While Row < 99
GoExcel.CellValue(Column & Row) = "" 'Value
Row = Row+1
End While

GoExcel.Save

GoExcel.Close

Should be easy enough for you to change the string values to look for the correct workbook.