Make sure you are not double-clicking. It is select the pipe with first click, which really selects the pipe run alignment. Pause. Select the pipe again. This time the selection changes from the alignment to the pipe and you can grip edit or disconnect or whatever you want to do. Disconnect will not break the association with the pipe run alignment. I think (pipe runs are a little shaky IMO).
But I am running 2022 also and also do not see grips on the pipe when selected by the above method. Not when it is connected, or when it is disconnected.A couple ways you may accomplish what you need - use AutoCAD MOVE command to move the pipe (and break the association) at which time you see the usual grips. But with the association to the run being lost you lose functionality to adjust the run by using the alignment (horz & vert) grips.
Another way is to break the pipe. This also breaks the alignment and creates a new alignment and a new pipe run.
How you proceed is what you are trying to accomplish. If you plan to use pipe runs try to get it right from the very start because the association being lost, or the pipe run disappearing (not the parts, but the run and any association to the horz and vert alignments) will happen.
Pipe runs are a great idea but unstable, IMO. I think there are certain rules that if broken break the run or disappear it. Unfortunately we learn the rules the hard way - by trial and error. Their strength is in adding vertical offsets with bends to get around other utilities. I try to get this done first because eventually the run is going to disappear - like adding a reducer to switch pipe size so we can add a temporary flushing hydrant - I guarantee this breaks it.
hth