Are you planning to use the scanned image as part of your final deliverable? If so, yes, you can bring the image in and scale it up so that it is twice its native size (assuming that the original drawing and the scanned image remain at a true 1/8" = 1'-0".
Typically, in AutoCAD, things are drawn in Model Space in "real world" dimensions. So a door opening that is 3'-0" wide in real life is drawn 3'-0" wide. The final output is then set up on one or more Layouts, where Paper Space is treated as the full size "paper", and scaled viewports are added to view the contents of Model Space at a particular scale. So if your final deliverable is a presentation board that is 42" long and 30" high, a rectangle for the trim line would be drawn that is 42" x 30" and the viewports and other graphics arranged inside. You can still do this with your image; you will just need to enlarge it to full size in Model Space.
If I were doing this, I would probably scale the image full size, and draw over it with AutoCAD elements, to get better graphic quality out of it for the final deliverable. If the 1/8" = 1'-0" plan drawing has sufficient dimensions on in, I might skip scanning the image and just re-draft the plan in AutoCAD.
David Koch
AutoCAD Architecture and Revit User
Blog | LinkedIn
