If you add it to your acad.lsp to load or in the startup suite it will load every time. Also make sure it is in the support file search path.
I have used similar lisps and made a small addition to it. If you notice it changes the qleader to the current mleader style. We have 6 different mleader styles we use so I added a setting of the mleader style and just modified the defun for which style I wanted. ex. 4" text = l2m4, 3" = l2m3, etc.
(defun c:L2M4 ()
(setvar "cmleaderstyle" "your Multileader style name here")