I have had some questions recently where people wanted to confirm that they had a fresh install.
Here are the directories that you need to delete to be close to a fresh install. Only delete these folders AFTER you have performed a standard uninstall using either the Autodesk Quick Uninstall utility or the Window Uninstall control panel. Make sure you backup and custom material database files.
C:\Program Files\Autodesk\Simulation CFD XXX 20XXX
C:\Users\%USERNAME%\AppData\Local\Temp\Autodesk Simulation CFD XXX 20XXX
C:\ProgramData\Autodesk\Simulation CFD XXX 20XXX
Extra Sim360 Pro Componenets
C:\Program Files\Autodesk\Simulation Job Manager 20XX
C:\ProgramData\Autodesk\Simulation Job Manager