Creating a local copy of the central seems to have helped. We work in one firm so there was no need to detach it from central. However, I have found that if I was to copy over the Architectural central file, lets say in the middle of the day to see the latest changes, and try and do a reload. Revit MEP does not like that at all. And gave an error I have never seen before, telling me the file is corrupt and I need to contact Autodesk. If I get out of the MEP file and then copy over the Architectural and reopen my MEP file, everything is fine, but this is a 20 minute process to open the file.