Try "nudging" a light fixture in the room, select the fixture and press the arrow key and then the other direction to move it back. That should re-calculate the lighting values.
I suspect we are not reacting to the change of the Family Parameter for the IES Data File, which is something I can pass on to the development team. I suspect you'll get the desired behavior if you actually create a new Type of the Family that uses the different IES Data file. I know our calcs react to a Type Change in the room.
Cheers,
Kyle B
Revit MEP Product Manager
http://inside-the-system.typepad.com/
Kyle Bernhardt
Director
Building Design Strategy
Autodesk, Inc.