Under your Web Extensions install in your mapviewernet folder there is a measure.aspx or an equivalent in php or jsp.
This is for the Basic Web Layout. You can scroll down in the file and see where it decides on kilometers or miles and edit this so that the default is inches. This would be a server wide change for all layouts. I've never done this so I don't know if more changes are required, but you can start here.
Regards,
Dave