1. Check the ODBC connection. In that connection, you'll specify the database and have the option to "test the connection". If that works, your problem isn't there.
2. In the Facility Request folder (mine is located here locally: "C:\Inetpub\wwwroot\FacilityRequest") take a look at the "Configure.xml" file. Make sure that the name you used in the ODBC connection is the same. SQL and Oracle will require the username / passwords as well.
3. Make sure the folder (where your database is located [back end database for access / middleware for SQL & Oracle]) is shared and security is enabled (read / write / execute) for the Internet Guest Account.
4. Make sure the database itself (middleware in the SQL & Oracle Versions) is shared and given the same permissions as 3 above. You can not simply allow the permissions to permiate from the folder above.
If all of that is working, try browsing through IIS first. Right click on the default.asp file in IIS and select Browse. If that doesn't display, there are more permissions to check, but hopefully that gives you some insight.