I've asked this before, but didnt get much of response.... but had some leeway on those lines.
This needs to work out as it will be a hard fit fabrication piece.
The header is pitched, and I am trying to connect to the main feed. No matter what I do I cannot get the two to connect.
Can you post the drawing in question to this forum (just the portion that you are having a problem with)? I can give you some suggestions but it would be easiest if I have the same setup that you have so I can help you figure this out.
You should use autoconnect to connect header to the main. Below is a small video that i created by tapping off the main. The trick is set your slope to 0 when drawing the vertical portions of the run and back to sloped when running the horizontal portions of the run.