The issue is temporary freezing leading to "not responding" during regens. The files I notice this as being the greatest problem have multiple paper space tabs for different drawing sheets with a shared base drawing Xref in model space. Switching between tabs, or between any paper space tab and model space, triggers a long regen that freezes, and will only continue if after a few seconds I pick a point on the screen, sending it to "not responding" mode, and then it will likely recover in 10-15 seconds. However, If I do not pick a screen point at some time, it will just remain frozen.
I am running LT 2010 on a laptop, we have a server environment but each installation of AutoCAD is stand-alone and does not reference the server for anything except shared pen tables, plot styles, etc. My laptop has over 150 GB free space on the drive.
Is there a memory cache setting somewhere that I might need to expand, or something similar? This seems to happen predominately with multiple-tabs in paper space, which I like to use when possible.