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As of r2016 the LAYISO command no longer has a settings variable. The LAYLOCKFADECTL variable can be used to fade other layers as much as 90%, but not completely.
I am still struggling to figure out how to make other layers disappear completely instead of fading and locking.
I'm using 2018. When I type LAYISO, then S, it give the options to be "Off" and "Lock and fade". If you hit "Off", it turns it off completely. "Lock and fade" gives you the option of a percent fade.
I am seeing it now. I don't know why it wasn't coming up for awhile. I am working with a fresh install, and seeing it now. Thanks!