Are you saving to your workspace after you "fix it"? Normally it is what you have to do when you change around screen objects.
If you answered yes, then your startup is replacing your profile/menu/workspace with a predefined one someone else decided you needed.
Post back and clarify.
I do not know about the original poster but the problem I have is that it is NOT keeping the change. If there is some hidden 'magic' button that has been added to R2012 then let us know because this is extremely annoying.
I just started having this issue as well. I first thought that I could just force the setvar to force the TPSTATE variable to '1' every time AutoCAD is opened, but it tells me that it ignored it or something. Any more ideas?