I realize this is an old post but as a recent search it's still relevant today with release 2012 AutoCAD. My question to all that have had or are having this issue is; are your servers Novell based? If so how much free space did you have on the server when the problem occurred? We currently have Novell servers and find that this problem occurs when the servers are close to being out of space. It seems that Novell will run in a compressed mode until there is enough free space for it to operate normally. To elaborate Novell will take an accessed file and uncompress it to make it available to the requesting client (workstation). Since AutoCAD manipulates the file at the workstation the file in essence is static on the server. This is why you can still save your AutoCAD file locally if you lose your network connection but would lose an Excel or Word file that was on the network. If the server was low on space and someone else accesses a file on the server it will see the other file as being static and recompress it to allow the other file or files to be accessed. When its time to save the file it seems we end up in this server workstation chaos. As a note I am not an IT guy but a very experienced AutoCAD abuser like the rest of you.
Thank you in advance for reading and possibly responding to my post.
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